Paul H A Quax Selected Research

Apolipoprotein E3

12/2020	Assessment of Microvessel Permeability in Murine Atherosclerotic Vein Grafts Using Two-Photon Intravital Microscopy.
10/2020	Effects on cardiac function, remodeling and inflammation following myocardial ischemia-reperfusion injury or unreperfused myocardial infarction in hypercholesterolemic APOE*3-Leiden mice.
1/2020	P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.
1/2020	Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice.
1/2020	bFGF blockade reduces intraplaque angiogenesis and macrophage infiltration in atherosclerotic vein graft lesions in ApoE3*Leiden mice.
9/2011	The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
8/2010	6-mercaptopurine inhibits atherosclerosis in apolipoprotein e*3-leiden transgenic mice through atheroprotective actions on monocytes and macrophages.

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Paul H A Quax Research Topics

Disease

27	Atherosclerosis 04/2021 - 05/2006
22	Ischemia 06/2022 - 07/2004
19	Inflammation (Inflammations) 10/2020 - 03/2005
12	Atherosclerotic Plaque (Atheroma) 12/2021 - 01/2012
12	Neointima 01/2020 - 05/2002
10	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 09/2007
8	Vascular Remodeling 01/2021 - 04/2010
8	Hyperplasia 01/2020 - 05/2002
7	Pathologic Constriction (Stenosis) 01/2022 - 12/2005
6	Thrombosis (Thrombus) 01/2021 - 03/2003
5	Neoplasms (Cancer) 04/2021 - 10/2005
5	Infarction (Infarctions) 01/2021 - 01/2018
4	Hypoxia (Hypoxemia) 01/2022 - 04/2013
4	Myocardial Ischemia (Ischemic Heart Diseases) 12/2020 - 01/2018
4	Reperfusion Injury 12/2020 - 01/2018
4	Abdominal Aortic Aneurysm 01/2018 - 04/2004
3	Central Serous Chorioretinopathy 01/2022 - 11/2018
3	Hemorrhage 01/2022 - 05/2013
3	Myocardial Infarction 04/2021 - 09/2011
3	Carotid Stenosis (Carotid Artery Stenosis) 12/2019 - 12/2013
3	Arteriovenous Fistula 06/2018 - 01/2016
3	Rupture 10/2014 - 01/2012
3	Coronary Disease (Coronary Heart Disease) 02/2012 - 09/2005
3	Vascular System Injuries 01/2011 - 05/2002
2	Heart Failure 01/2022 - 08/2019
2	Ischemic Stroke 12/2020 - 11/2015
2	Chronic Limb-Threatening Ischemia 01/2020 - 01/2018
2	Coronary Artery Disease (Coronary Atherosclerosis) 01/2016 - 01/2015
2	Arterial Occlusive Diseases (Arterial Occlusive Disease) 03/2014 - 07/2004
1	Aortic Aneurysm (Aneurysm, Aortic) 04/2021
1	Hereditary Hemorrhagic Telangiectasia 02/2021
1	Vascular Malformations 02/2021
1	Pulmonary Hypertension 01/2021
1	Stroke (Strokes) 12/2020
1	Cerebral Hemorrhage 12/2020

Drug/Important Bio-Agent (IBA)

17	MicroRNAs (MicroRNA)IBA 06/2022 - 08/2009
13	Apolipoproteins E (ApoE)IBA 01/2022 - 08/2007
7	Apolipoprotein E3IBA 12/2020 - 08/2010
5	Biomarkers (Surrogate Marker)IBA 12/2020 - 02/2012
5	Pharmaceutical PreparationsIBA 11/2017 - 12/2005
4	CholesterolIBA 01/2020 - 01/2017
3	Messenger RNA (mRNA)IBA 01/2022 - 12/2005
3	Phosphorylcholine (Phosphocholine)IBA 01/2021 - 04/2020
3	ApolipoproteinsIBA 10/2020 - 07/2009
3	LipidsIBA 01/2020 - 08/2013
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 01/2020 - 12/2002
3	Interleukin-10 (Interleukin 10)IBA 01/2018 - 08/2007
3	Phenobarbital (Luminal)FDA Link 01/2017 - 08/2012
3	Small Interfering RNA (siRNA)IBA 01/2014 - 07/2009
3	CytokinesIBA 04/2013 - 04/2010
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2011 - 05/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2007 - 12/2002
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2022 - 08/2012
2	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2022 - 01/2022
2	Antisense OligonucleotidesIBA 12/2021 - 12/2019
2	matrigelIBA 08/2021 - 01/2020
2	EndoglinIBA 04/2021 - 02/2021
2	AntibodiesIBA 01/2021 - 12/2020
2	Immunoglobulin G (IgG)IBA 12/2020 - 01/2014
2	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 11/2020 - 01/2020
2	Adenosine (Adenocard)FDA LinkGeneric 09/2020 - 01/2018
2	Inosine FDA Link 09/2020 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 02/2010
2	Immunoglobulin E (IgE)IBA 01/2019 - 01/2014
2	Annexin A5IBA 01/2018 - 01/2011
2	Complementary DNA (cDNA)IBA 01/2018 - 08/2007
2	ChemokinesIBA 03/2017 - 08/2015
2	garcinolIBA 01/2017 - 08/2013
2	Lysine AcetyltransferasesIBA 01/2017 - 01/2011
2	Toll-Like Receptor 4IBA 01/2015 - 01/2014
2	Complement System Proteins (Complement)IBA 10/2014 - 02/2013
2	Biological ProductsIBA 01/2013 - 02/2012
2	Matrix Metalloproteinases (MMPs)IBA 01/2012 - 10/2005
2	Tissue Inhibitor of Metalloproteinase-1IBA 01/2012 - 02/2010
2	PolymersIBA 08/2011 - 12/2005
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2011 - 07/2010
2	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 01/2011 - 02/2010
2	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 08/2010 - 01/2007
2	LipopolysaccharidesIBA 08/2010 - 10/2002
2	Dexamethasone (Maxidex)FDA LinkGeneric 04/2006 - 12/2005
2	CollagenIBA 12/2005 - 04/2004
2	Tissue Inhibitor of Metalloproteinase-3IBA 10/2005 - 05/2005
1	6-methyladenineIBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2021
1	Transfer RNA (tRNA)IBA 12/2020
1	Dextrans (Dextran)FDA Link 12/2020
1	salicylhydroxamic acid (SHAM)IBA 10/2020
1	MyostatinIBA 05/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 04/2020

Therapy/Procedure

16	Therapeutics 01/2021 - 07/2004
4	Percutaneous Coronary Intervention 10/2020 - 12/2005
4	Stents 08/2011 - 04/2004
3	Endarterectomy (Thromboendarterectomy) 01/2021 - 11/2015
3	Ligation 10/2020 - 01/2004
2	Lasers (Laser) 11/2021 - 01/2014
2	Operative Surgical Procedures 07/2019 - 02/2016
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2016 - 06/2006
2	Drug-Eluting Stents 05/2006 - 03/2005
1	Treatment Delay 12/2020
1	Investigational Therapies (Experimental Therapy) 10/2020